Psst! I've posted some details about my notebook setup here.

A brief review of HULK and histosketch

About a month ago, I was intrigued to see a bit of Twitter activity around a new bioRxiv preprint. The manuscript describes HULK, a new bioinformatics tool that implements some useful comparison metrics and operations for analyzing (meta)genomes. HULK is based on a new algorithm called histogram sketching (HistoSketch for short), following the trend of related sketching algorithms (HyperLogLog …

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